The following bibliography of published peer reviewed articles includes uses for our technology within the specific indications for facial dermal resurfacing. This is intended to be a forum for scientific exchange and thus this content may include unapproved uses. Not all markets have the same labeling, refer to the local Instructions for Use or contact your local representative for more information. All investigator disclosures are within the publications.

Renuvion® Dermal Handpiece is indicated for dermatological procedures for the treatment of moderate to severe wrinkles and rhytides, limited to patients with Fitzpatrick skin types I, II, or III. Warning: Application of more than one treatment pass in the perioral area, on the forehead, and along the jawline has been associated with hypertrophic scarring. Risks associated with the use of the Renuvion Dermal System include but are not limited to hypertrophic scarring, milia/acne, telangiectasia (spider veins), skin discoloration/hypopigmentation, dormant infection reactivation, infection, bruising or bleeding. As with any procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use, refer to the IFU for further information.

1. Canter HI, Ismayilzada M. Minimally Invasive Treatments for the Aging Face. Academic Press, Beauty, Aging, and AntiAging, 2023, Pages 211-221. https://doi.org/10.1016/B978-0-323-98804-9.00021-9
2. DeLozier JB, Holcomb JD. Helium Plasma Dermal Resurfacing With and Without Concurrent Aesthetic Surgery of the Face and Neck: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac061, https://doi.org/10.1093/asjof/ojac061
3. Gentile RD. Plasma Energy Skin Rejuvenation. Advances in Cosmetic Surgery, Vol 3, Iss 1, June 2020, Pages 39-50.
4. Gentile RD. Renuvion®/J-Plasma® for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001
5. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.
6. Gentile R. Tesla Facelifting Using Energy Devices during Rhytidectomy. Facial Plast Surg 2022; 38(06): 668-678. DOI: 10.1055/s-0042-1757758
7. Gentile RD. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.
8. Gentile R. Ultrasound-Assisted Rhytidectomy Including Sub-SMAS and Subplatysmal Dissection. Facial Plast Surg 2020; 36(04): 430-446. DOI: 10.1055/s-0040-1714119.
9. Gentile RD, McCoy JD. Pulsed and Fractionated Techniques for Helium Plasma Energy Skin Rejuvenation. Facial Plast Surg Clin North Am. 2020 Feb;28(1):75-85. doi: 10.1016/j.fsc.2019.09.007.
10. Holcomb JD. Helium plasma dermal resurfacing: VISIA CR assessment of facial spots, pores, and wrinkles – Preliminary findings. JCD 26 Mar 2021. https://doi.org/10.1111/jocd.14106.
11. Holcomb JD. Plasma Energy Skin Rejuvenation. Facial Plast Surg Clin North Am. 2020 Feb;28(1):67-74. doi: 10.1016/j.fsc.2019.09.006.
12. Holcomb JD, Doolabh V, Lin M, Zimmerman E. High energy, double pass helium plasma dermal resurfacing: A prospective, multicenter, single-arm clinical study. Lasers Surg Med. 2022 Feb 16. doi: 10.1002/lsm.23524. Epub ahead of print. PMID: 35170772.
13. Holcomb JD, Duncan D, Lin M, et al. Helium plasma dermal resurfacing: Consensus guidelines. Dermatological Reviews. 2020;1–11. https://doi.org/10.1002/der2.22
14. Holcomb JD, Kelly M, Hamilton TK, and DeLozier JB. A Prospective Study Evaluating the Use of Helium Plasma for Dermal Resurfacing. Lasers in Surgery and Medicine, 2020 Apr 29. DOI: 10.1002/lsm.23257.
15. Holcomb, J.D. and Schucker, A. (2020), Helium Plasma Skin Regeneration: Evaluation of Skin Tissue Effects in a Porcine Model and Comparison to Nitrogen Plasma Skin Regeneration. Lasers Surg. Med., 52: 23-32. https://doi.org/10.1002/lsm.23167
16. Lacerna Kimbrell M. Take your facelifts to the next level: safety and efficacy of PLASMA resurfacing with face and necklifts. Plast Reconstr Surg Glob Open. 2024;12(S8):2-3. doi:10.1097/01.GOX.0001063824.26292.03.
17. Leake D, Lee J. Applications of Helium Plasma in Rejuvenation of the Face and Neck [Internet]. Enhanced Liposuction – New Perspectives and Techniques. IntechOpen; 2022. Available from: http://dx.doi.org/10.5772/intechopen.100162
18. Lotfi M, Khani M, Shokri B. A Review of Cold Atmospheric Plasma Applications in Dermatology and Aesthetics. Plasma Medicine, Volume 13, Issue 1, 2023, pp. 39-63. DOI: 10.1615/PlasmaMed.2023049359.
19. Paul G Ruff IV. Evaluation of Skin Tissue Effects of Two-Pass Helium Plasma Treatment in Comparison to Nitrogen Plasma Using A Swine Model. Biomed J Sci & Tech Res 34(2)-2021. BJSTR. MS.ID.005512.
20. Sweitzer K, Obagi Z, Rahman T, Koltz PF, Barone F (2021) The Safety and Efficacy of Helium-Based Plasma for Cutaneous Resurfacing and Subdermal Tightening. J Aesthet Reconstr Surg Vol.7 No.5:40.