The following bibliography of published peer reviewed articles includes all uses of our technology. This is intended to be a forum for scientific exchange and thus this content may include unapproved uses. Not all markets have the same labeling, refer to the local Instructions for Use or contact your local representative for more information. All investigator disclosures are within the publications.

The Renuvion® APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma where coagulation/contraction of soft tissue is needed. Soft tissue includes subcutaneous tissue. The Renuvion APR Handpiece is intended for the coagulation of subcutaneous soft tissues following liposuction for aesthetic body contouring. The Renuvion APR Handpiece is indicated for use in subcutaneous dermatological and aesthetic procedures to improve the appearance of lax (loose) skin in the neck and submental region. The Renuvion APR Handpiece is intended for the delivery of radiofrequency energy and/or helium plasma for cutting, coagulation and ablation of soft tissue during open surgical procedures. The Renuvion APR Handpiece is intended to be used with compatible electrosurgical generators owned by Apyx® Medical. Not all indications are approved in all markets; check with your local sales representative for further information.

As with any aesthetic procedure, individual results may vary. As with all energy devices there are inherent risks associated with its use. Risk associated with the use of the Renuvion APR may include: helium embolism into the surgical site due to inadvertent introduction into the venous or arterial blood supply system, unintended burns (deep or superficial), pneumothorax, temporary or permanent nerve injury, ischemia, fibrosis, infection, pain, discomfort, gas buildup resulting in temporary and transient crepitus or pain, bleeding, hematoma, seroma, subcutaneous induration, pigmentation changes, increased healing time, scarring, asymmetry and/ or unacceptable cosmetic result. Please see the instructions for use for more detailed information.

ABDOMEN, TORSO, BUTTOCKS CONTOURING

1. Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445
2. Barone M, Salzillo R, De Bernardis R, et al. Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in Patients Undergoing Abdominoplasty After Massive Weight Loss: A Prospective Controlled Randomized Study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-024-04655-1
3. Brummund D, Husain T. Abdominal etching with Renuvion helium plasma. Aesthet Surg J Open Forum. 2024;6(Suppl 1):ojae007.074. doi:10.1093/asjof/ojae007.074.
4. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.
5. De La Cruz E, Delacruz BP. Reducing risks in large volume liposuction: the role of oral anticoagulants in preventing thromboembolism. J Hematol Thrombo Dis. 2024;12:593.
6. De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.
7. Kleban SR, Bharti G, & Kortesis BG. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398
8. Nichols C, Albershardt D. Tissue contraction with helium-based plasma radiofrequency technology: a preliminary report of initial ultrasound findings. Aesthet Surg J Open Forum. 2024;6:ojae104. doi:10.1093/asjof/ojae104.
9. Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301
10. Tambasco D, Scarabosio A, Tomaselli F, et al. The role of helium plasma-assisted liposuction in lipoabdominoplasty after weight loss. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04542-9.
11. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153
12. Vanek P. A retrospective evaluation of the safety of combining helium-based plasma radiofrequency technology with ultrasound-assisted lipoabdominoplasty. Aesthet Surg J Open Forum. 2025;7:ojae116. doi:10.1093/asjof/ojae116.
13. Zimmerman, Edward. “Posterior Torso and Buttocks Contour Enhancement”. Enhanced Liposuction – New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

AESTHETIC BODY CONTOURING FOLLOWING LIPOSUCTION

1. Akkary, E. (2022). Use of J Plasma® in Body Contouring. In: Thomas, M., D’silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_18

2. Arshad S, Sin Z, Flores D, Satey S, Mowlavi A. Brazilian Buttock Lift for the Weight-Loss Patient. The American Journal of Cosmetic Surgery. March 2022. doi:10.1177/07488068221079445

3. Brummund D, Husain T. Abdominal etching with Renuvion helium plasma. Aesthet Surg J Open Forum. 2024;6(Suppl 1):ojae007.074. doi:10.1093/asjof/ojae007.074.

4. Bruno A, Cilluffo M. The role of helium plasma technology in liposuction for lipedema of the lower limbs: a stage-specific analysis. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-05407-5

5. Cook J, Pozner JN, Turer DM, et al. Roundtable Discussion: Making Sense of Current Liposuction Technologies. Aesthet Surg J Open Forum. 2021;4:ojab045. Published 2021 Nov 9. doi:10.1093/asjof/ojab045

6. Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.

7. Danilla S, Abou-Kheir N, Gonzalez R, et al. The fourth-generation lower body lift: combining techniques and technologies for improved outcomes in high-demand female patients. Aesthetic Plastic Surgery. 2025;49:3121–3131. doi:10.1007/s00266-025-04877-x

8. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.

9. De La Cruz E, Delacruz BP. Reducing risks in large volume liposuction: the role of oral anticoagulants in preventing thromboembolism. J Hematol Thrombo Dis. 2024;12:593.

10. De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.

11. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

12. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

13. Duncan DI. Helium Plasma-Driven Radiofrequency in Body Contouring. The Art of Body Contouring. Published March 8, 2019. DOI: 10.5772/intechopen.84207.

14. Duncan, Diane. (2020). Combining Helium Plasma-Driven Radiofrequency with Nanofat for Contouring. 10.5772/intechopen.91611.

15. Duncan, DI. The future of skin tightening: Mechanical or biological? Dermatological Reviews. 2020; 1: 128- 137. https://doi.org/10.1002/der2.40

16. Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001

17. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

18. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

19. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

20. Ghani S. Review of non-invasive and minimally invasive skin tightening techniques. Journal of Aesthetic Nursing 2019 8:Sup1, 26-33.

21. Hamlet, G., Mowlavi, A. (2022). Hi-Def Liposuction in Males and Females. In: Thomas, M., D’silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_13

22. Hoyos AE, Perez ME, Mogollon IR, Arcila A. Decision-Making Algorithm for Advanced Excisional Body Contouring: Dynamic Definition Solutions for Skin Laxity. Plast Reconstr Surg. 2022 Dec 1;150(6):1248-1259. doi: 10.1097/PRS.0000000000009740. Epub 2022 Sep 19. PMID: 36112807.

23. Hoyos AE, Perez ME, Cala LC, Dominguez R, Vranis NM, Dayan E. Helium plasma-driven radiofrequency for skin contraction: clinical use, safety recommendations, and results in Hi-Def body contouring surgery. Aesthet Surg J Open Forum. 2025;ojae118. doi:10.1093/asjof/ojae118.

24. Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031

25. Jugenburg, M., Jalil, W. (2022). Liposuction: Principles and Techniques. In: Thomas, M., D’silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_4

26. Khanna, J., & Saheb-Al-Zamani, M. (2021). Enhanced Lipocontouring of the Arms. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.98807

27. Khedr MM, Elshawadfy SE. Scarless enhanced body contouring. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04401-7.

28. Kleban, S. R. , Bharti, G., & Kortesis, B. G. (2021). Enhanced Abdominal Contouring. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99398

29. Kluska M, Deal RC, Summers K, Chang S. A Retrospective Review Comparing Renuvion Helium Plasma Radiofrequency with BodyTite Bipolar Radiofrequency after Liposuction or Body Contouring. Plastic & Reconstructive Surgery-Global Open 12(8):p e6024, August 2024. | DOI: 10.1097/GOX.0000000000006024

30. Malone, C.H., Walters, N., Stroh, R. et al. New Technologies in Skin Tightening. Curr Otorhinolaryngol Rep 9, 422–435 (2021). https://doi.org/10.1007/s40136-021-00371-5

31. Mata, C., Gadayev, M., Ferrara, G.P., Kesserwani, J. (2022). Hi- Def Liposuction- My Technique. In: Thomas, M., D’silva, J. (eds) Manual of Cosmetic Surgery and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-4997-5_12

32. Neinstein R, Funderburk CD. Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency. Advances in Cosmetic Surgery, Volume 3, Issue 1, 2020, Pages 173-188, ISSN 2542-4327, ISBN 9780323778282. https://doi.org/10.1016/j.yacs.2020.01.012.

33. Nichols C, Albershardt D. Tissue contraction with helium-based plasma radiofrequency technology: a preliminary report of initial ultrasound findings. Aesthet Surg J Open Forum. 2024;6:ojae104. doi:10.1093/asjof/ojae104.

34. Palmisano E, Di Biasio G. Minimally invasive management alternative for the treatment of patients with abdominal diastasis and dermal fat flap using the VER tactic: Vaser® + Endoscopy + Renuvion®. Rev Hispanoam Hernia. 2022;10(4):167-171

35. Ruff PG, Martinez A, Burpee N. Refining liposuction safety and efficacy: surgeon learning-curve analysis with helium-based plasma integration. Aesthet Surg J Open Forum. 2024;6:ojae063. doi:10.1093/asjof/ojae063.

36. Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

37. Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

38. Shantharam R, et al., J Clin Dermatol Ther 2023, 9: 0128 DOI: 10.24966/CDT-8771/100128

39. Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081

40. Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112

41. Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301

42. Tambasco D, Albanese R, Tomaselli F, Pinto V, Pinelli M, De Santis G. Minimizing thighplasty complications: a combined approach of J-medial pattern and helium plasma–assisted liposculpture. Plast Reconstr Surg. 2025;156(2):247-251

43. Tambasco D, Albanese R, Scarabosio A, et al. Ultrasound and helium plasma-assisted liposuction for body contouring: a single-retrospective cohort study of 639 patients. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04367-6.

44. Thomas M, D’silva J, Abraham A. (2021). Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99947

45. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153

46. Troell RJ. Liposuction 20-year learned experience (part 2): optimizing cosmetic outcomes while minimizing complications. Am J Cosmet Surg. 2025;0(0). doi:10.1177/07488068251352069

47. Vasilakis, V., Isakson, M.H., Yamin, F. et al. Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience. Aesth Plast Surg 44, 1596–1603 (2020). https://doi.org/10.1007/s00266-020-01857-1

48. Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2 (2019) 89-95. DOI: 10.1016/j.yacs.2019.02.008.

49. Zimmerman, Edward. “Posterior Torso and Buttocks Contour Enhancement”. Enhanced Liposuction – New Perspectives and Techniques, edited by Diane Duncan, IntechOpen, 2021. 10.5772/intechopen.100529.

ARMS

1. Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.

2. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

3. Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031

4. Khanna, J., & Saheb-Al-Zamani, M. (2021). Enhanced Lipocontouring of the Arms. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.98807

5. Shantharam R, et al., J Clin Dermatol Ther 2023, 9: 0128 DOI: 10.24966/CDT-8771/100128

6. Vasilakis, V., Isakson, M.H., Yamin, F. et al. Four-Position Four-Entry Site Circumferential Arm Liposuction: Technique Overview and Experience. Aesth Plast Surg 44, 1596–1603 (2020). https://doi.org/10.1007/s00266-020-01857-1

BREAST

1. Moncada S, Nichols C. Helium Plasma-Assisted Breast Reduction: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac041, https://doi.org/10.1093/asjof/ojac041

2. Sterodimas A. Helium plasma effect on breast stromal-enriched lipograft: a case report. Aesthet Surg J Open Forum. 2024;6:ojae087. doi:10.1093/asjof/ojae087.

3. Sterodimas A, Moutafis A, Nicaretta B, Champsas G. A prospective study on helium-based plasma radiofrequency for minimally invasive breast lift scarless mastopexy. Aesthet Surg J Open Forum. 2025;ojaf004. doi:10.1093/asjof/ojaf004.

CLINICAL STUDIES

1. Barone M, Salzillo R, De Bernardis R, et al. Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in Patients Undergoing Abdominoplasty After Massive Weight Loss: A Prospective Controlled Randomized Study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-024-04655-1

2. Bruno A, Cilluffo M. The role of helium plasma technology in liposuction for lipedema of the lower limbs: a stage-specific analysis. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-05407-5

3. Cuzalina, et. al. A Retrospective Study to Evaluate the Efficacy of a Plasma Energy System (Renuvion®) in the Management of Skin Laxity to Improve Tightening at the Time of Standard Liposuction of the Arms. AJCS. July 2021. DOI:10.1177/07488068211031096.

4. Danilla S, Abou-Kheir N, Gonzalez R, et al. The fourth-generation lower body lift: combining techniques and technologies for improved outcomes in high-demand female patients. Aesthetic Plastic Surgery. 2025;49:3121–3131. doi:10.1007/s00266-025-04877-x

5. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.

6. De Souza AST, De Souza AC (2022) Brazilian Butt Lift Procedures when the Renuvion APR System was used as an Adjunct Procedure: A Retrospective Chart Review. J Aesthet Reconstr Surg Vol.8 No.4:150.

7. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

8. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

9. Ibrahiem SMS, MD, MRCS, EBOPRAS, Aesthetic Nonexcisional Arm Contouring, Aesthetic Surgery Journal, 2022;, sjac031, https://doi.org/10.1093/asj/sjac031

10. Kluska M, Deal RC, Summers K, Chang S. A Retrospective Review Comparing Renuvion Helium Plasma Radiofrequency with BodyTite Bipolar Radiofrequency after Liposuction or Body Contouring. Plastic & Reconstructive Surgery-Global Open 12(8):p e6024, August 2024. | DOI: 10.1097/GOX.0000000000006024

11. Lacerna Kimbrell M. Helium plasma radiofrequency brow lift: description of a novel technique and retrospective study on safety, efficacy, and durability. Aesthet Surg J Open Forum. 2025;ojaf031. doi:10.1093/asjof/ojaf031

12. Leake D, Lee J. Applications of Helium Plasma in Rejuvenation of the Face and Neck [Internet]. Enhanced Liposuction – New Perspectives and Techniques. IntechOpen; 2022. Available from: http://dx.doi.org/10.5772/intechopen.100162

13. Moncada S, Nichols C. Helium Plasma-Assisted Breast Reduction: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac041, https://doi.org/10.1093/asjof/ojac041

14. Nichols C, Albershardt D. Tissue contraction with helium-based plasma radiofrequency technology: a preliminary report of initial ultrasound findings. Aesthet Surg J Open Forum. 2024;6:ojae104. doi:10.1093/asjof/ojae104.

15. Ouf MAA, Kishk TFA, Elnahas MA. Evaluation of traditional liposuction, VASER liposuction, and VASER liposuction combined with J-plasma in management of gynecomastia. Plast Reconstr Surg Glob Open. 2024;12(11):e6277. doi:10.1097/GOX.0000000000006277.

16. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

17. Ruff PG, Doolabh V, Zimmerman E, Gentile R. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews 2020; 1-7. https://doi.org/10.1002/der2.34

18. Ruff PG IV, Martinez A. Evaluation of the use of the Renuvion system in the labia for labial rejuvenation and volume reduction. J Gynecol Surg. Published online September 29, 2025. doi:10.1177/1042406725138286

19. Ruff PG, Martinez A, Burpee N. Refining liposuction safety and efficacy: surgeon learning-curve analysis with helium-based plasma integration. Aesthet Surg J Open Forum. 2024;6:ojae063. doi:10.1093/asjof/ojae063.

20. Ruff PG, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

21. Ruff PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

22. Shantharam R, et al., J Clin Dermatol Ther 2023, 9: 0128 DOI: 10.24966/CDT-8771/100128

23. Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081

24. Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112

25. Sterodimas A, Moutafis A, Nicaretta B, Champsas G. A prospective study on helium-based plasma radiofrequency for minimally invasive breast lift scarless mastopexy. Aesthet Surg J Open Forum. 2025;ojaf004. doi:10.1093/asjof/ojaf004.

26. Sterodimas A, Nicaretta B, Koytsouveli A, et al. Helium-based plasma radio frequency technology for subdermal coagulation in the forehead: a preliminary, single-center retrospective study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-04737-8.

27. Tambasco D, Albanese R, Tomaselli F, Pinto V, Pinelli M, De Santis G. Minimizing thighplasty complications: a combined approach of J-medial pattern and helium plasma–assisted liposculpture. Plast Reconstr Surg. 2025;156(2):247-251

28. Tambasco D, Scarabosio A, Tomaselli F, et al. The role of helium plasma-assisted liposuction in lipoabdominoplasty after weight loss. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04542-9.

29. Tambasco D, Albanese R, Scarabosio A, et al. Ultrasound and helium plasma-assisted liposuction for body contouring: a single-retrospective cohort study of 639 patients. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04367-6.

30. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153

31. Troell RJ, Javaheri S. Combining Third-Generation Ultrasound Liposuction With Helium-Based Plasma Technology Skin Tightening in the Face and Neck. The American Journal of Cosmetic Surgery. 2025;0(0). doi:10.1177/07488068251330030

32. Vanek P. A retrospective evaluation of the safety of combining helium-based plasma radiofrequency technology with ultrasound-assisted lipoabdominoplasty. Aesthet Surg J Open Forum. 2025;7:ojae116. doi:10.1093/asjof/ojae116.

33. Zorrilla AM, Sanchez-Covarrubias AP, Martin K, Rodriguez M. Pain Management and Opioid Consumption After Outpatient Cosmetic Surgery. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221116529

CONTRACTILE EFFECTS AND TISSUE REMODELING

1. Barone M, Salzillo R, De Bernardis R, et al. Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in Patients Undergoing Abdominoplasty After Massive Weight Loss: A Prospective Controlled Randomized Study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-024-04655-1

2. Canter HI, Ismayilzada M. Minimally Invasive Treatments for the Aging Face. Academic Press, Beauty, Aging, and AntiAging, 2023, Pages 211-221. https://doi.org/10.1016/B978-0-323-98804-9.00021-9

3. Dayan E, Theodorou S. Not all Radiofrequency Devices Are Created Equal: A Thermal Assessment. Plast Reconstr Surg Glob Open. 2022 Feb 4;10(2):e4077. doi: 10.1097/GOX.0000000000004077. PMID: 35141101; PMCID: PMC8820913.

4. Doolabh, Vaishali. (2021). Contractile Effects of Radiofrequency Energized Helium Plasma on the Fibrous Septal Network. 10.5772/intechopen.97849

5. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

6. Duncan DI. Helium Plasma-Driven Radiofrequency in Body Contouring. The Art of Body Contouring. Published March 8, 2019. DOI: 10.5772/intechopen.84207.

7. Duncan DI, Roman, S. Helium Plasma Subdermal Tissue Contraction Method of Action. BioMedical Journal of Scientific & Technical Research. October 19, 2020; DOI: 10.26717/BJSTR.2020.31.005075.

8. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

9. Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001

10. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

11. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

12. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

13. Nichols C, Albershardt D. Tissue contraction with helium-based plasma radiofrequency technology: a preliminary report of initial ultrasound findings. Aesthet Surg J Open Forum. 2024;6:ojae104. doi:10.1093/asjof/ojae104.

14. Ruff IV, PG. Thermal Effects of Percutaneous Application of Plasma/Radiofrequency Energy on Porcine Dermis & Fibroseptal Network. JCD, 2020. DOI: 10.1111/jocd.13845

15. Sterodimas A, Moutafis A, Nicaretta B, Champsas G. A prospective study on helium-based plasma radiofrequency for minimally invasive breast lift scarless mastopexy. Aesthet Surg J Open Forum. 2025;ojaf004. doi:10.1093/asjof/ojaf004.

16. Sterodimas A, Nicaretta B, Koytsouveli A, et al. Helium-based plasma radio frequency technology for subdermal coagulation in the forehead: a preliminary, single-center retrospective study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-04737-8.

17. Thomas M, D’silva J, Abraham A. (2021). Use of Technologies to Improve the Liposuction Outcome Including Skin Texture and Form. In (Ed.), Enhanced Liposuction – New Perspectives and Techniques. IntechOpen. https://doi.org/10.5772/intechopen.99947

18. Trott SA. Insights from submental plication four months following helium plasma radio frequency treatment. J Aesthet Reconstr Surg. 2024;10(4):167.

FACELIFT/NECKLIFT

1. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

2. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

3. Gentile RD. Tesla Facelifting Using Energy Devices during Rhytidectomy. Facial Plast Surg 2022; 38(06): 668-678. DOI: 10.1055/s-0042-1757758

4. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

5. Lacerna Kimbrell M. Helium plasma radiofrequency brow lift: description of a novel technique and retrospective study on safety, efficacy, and durability. Aesthet Surg J Open Forum. 2025;ojaf031. doi:10.1093/asjof/ojaf031

6. Lacerna Kimbrell M. Take your facelifts to the next level: safety and efficacy of PLASMA resurfacing with face and necklifts. Plast Reconstr Surg Glob Open. 2024;12(S8):2-3. doi:10.1097/01.GOX.0001063824.26292.03.

7. Sterodimas A, Nicaretta B, Koytsouveli A, et al. Helium-based plasma radio frequency technology for subdermal coagulation in the forehead: a preliminary, single-center retrospective study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-04737-8.

8. Trott SA. Insights from submental plication four months following helium plasma radio frequency treatment. J Aesthet Reconstr Surg. 2024;10(4):167.

FACE & NECK (SUBDERMAL TREATMENT)

1. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

2. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

3. Gentile RD. Renuvion®/J-Plasma for Subdermal Skin Tightening Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plast Surg Clin North Am. 2019;27(3):273–290. doi:10.1016/j.fsc.2019.03.001

4. Gentile RD. Renuvion RF-Helium Plasma for Subdermal Skin Tightening, Facial Contouring and Skin Rejuvenation of the Face and Neck. Facial Plastic Surgery & Aesthetic Medicine, Volume 22, Number 4, 2020.

5. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

6. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

7. Lacerna Kimbrell M. Helium plasma radiofrequency brow lift: description of a novel technique and retrospective study on safety, efficacy, and durability. Aesthet Surg J Open Forum. 2025;ojaf031. doi:10.1093/asjof/ojaf031

8. Leake D, Lee J. Applications of Helium Plasma in Rejuvenation of the Face and Neck [Internet]. Enhanced Liposuction – New Perspectives and Techniques. IntechOpen; 2022. Available from: http://dx.doi.org/10.5772/intechopen.100162

9. Lotfi M, Khani M, Shokri B. A Review of Cold Atmospheric Plasma Applications in Dermatology and Aesthetics. Plasma Medicine, Volume 13, Issue 1, 2023, pp. 39-63. DOI: 10.1615/PlasmaMed.2023049359.

10. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

11. Sterodimas A, Nicaretta B, Koytsouveli A, et al. Helium-based plasma radio frequency technology for subdermal coagulation in the forehead: a preliminary, single-center retrospective study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-04737-8.

12. Sturm A, Shokri T, Ducic Y. Nonsurgical Rejuvenation of the Neck. Facial Plast Surg Clin North Am. 2022 Aug;30(3):407-417. doi: 10.1016/j.fsc.2022.03.014. PMID: 35934442.

13. Troell RJ, Javaheri S. Combining Third-Generation Ultrasound Liposuction With Helium-Based Plasma Technology Skin Tightening in the Face and Neck. The American Journal of Cosmetic Surgery. 2025;0(0). doi:10.1177/07488068251330030

14. Trott SA. Insights from submental plication four months following helium plasma radio frequency treatment. J Aesthet Reconstr Surg. 2024;10(4):167.

15. Wang MW, Rodman RE. Gender Facial Affirmation Surgery; Techniques for Feminizing the Chin. Facial Plast Surg Clin North Am. 2023 Aug;31(3):419-431. doi: 10.1016/j.fsc.2023.04.006. PMID: 37348985.

16. Zamora J, Roman S. Subcutaneous Neck Skin Plasma Tightening. Advances in Cosmetic Surgery 2 (2019) 89-95. DOI: 10.1016/j.yacs.2019.02.008.

FAT GRAFTING

1. Ruff, PG., Sterodimas, A. Enhanced Fat Graft Viability and Remodeling Using a Helium-based Radiofrequency Device to Prepare the Recipient Site. Aesth Plast Surg (2023). https://doi.org/10.1007/s00266-023-03749-6

2. Sterodimas A. Helium plasma effect on breast stromal-enriched lipograft: a case report. Aesthet Surg J Open Forum. 2024;6:ojae087. doi:10.1093/asjof/ojae087.

GYNECOMASTIA

1. Ouf MAA, Kishk TFA, Elnahas MA. Evaluation of traditional liposuction, VASER liposuction, and VASER liposuction combined with J-plasma in management of gynecomastia. Plast Reconstr Surg Glob Open. 2024;12(11):e6277. doi:10.1097/GOX.0000000000006277.

2. Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

3. Tambasco D, Albanese R, Scarabosio A, et al. A three-dimensional approach to male chest enhancement: a surgical algorithm based on 300 cases. Aesthet Plast Surg. 2024;48:3646–3655. doi:10.1007/s00266-024-04063-5.

4. Filis K, Galyfos G, Sigala F, Zografos G. Utilization of Low-Temperature Helium Plasma (J-Plasma) for Dissection and Hemostasis during Carotid Endarterectomy. Journal of Vascular Surgery. March 2020, Volume 6, Issue 1, Pages 152-155.
5. Iavazzo C, Fotiou A, Kokkali K, Vorgias G. Experience With J-Plasma Device in Achieving Complete Cytoreduction in Patients With Ovarian Cancer. Cancer Diagn Progn. 2023 May 3;3(3):392-397. doi: 10.21873/cdp.10230. PMID: 37168972; PMCID: PMC10165381.
6. Jundt JS, Marchena JM, Hanna I, Dhanda J, Breit MJ, Perry AP. Evolving Technologies for Tissue Cutting. Oral Maxillofac Surg Clin North Am. 2019 Nov;31(4):549-559. doi: 10.1016/j.coms.2019.07.009. Epub 2019 Aug 31. PMID: 31481290.
7. Kyriazanos, et al. Total Extraperitoneal Access for Parietal Peritonectomy for Peritoneal Surface Malignancy: The ‘Cocoon’ Technique. European Journal of Obstetrics & Gynecology and Reproductive Biology. June 2020.
8. Llarena NC, Shah AB, Biscotti C, Falcone T, Uy-Kroh MJ. Thermal Injury to the Ovary and Uterus in a Porcine Model: A Comparison of Four Energy Sources. Clin. Exp. Obstet. Gynecol. – ISSN: 0390-6663XLVI, n. 6, 2019 doi: 10.12891/ceog5061.2019
9. Manuel M. Laparoscopic Treatment of Benign and Malignant Pelvic Disorders Utilizing Helium Plasma: A Retrospective Analysis. BioMedical Journal of Scientific & Technical Research. December 23, 2020. DOI: 10.26717/BJSTR.2020.32.005310.

10. Masghati S, Pedroso J, Gutierrez M, Stockwell E, Volker KW, Howard DL. Comparative Thermal Effects of J-Plasma, Monopolar, Argon, and Laser Electrosurgery in a Porcine Tissue Model. Surg Technol Int. 2019;34:35–39.

11. Mattei B, Colletti G, Negrello S, et al. Treating head and neck venous malformations with cold helium plasma electrosurgical device: A 17 patients case series. J Craniofac Surg. 2025. doi:10.1016/j.jcms.2025.02.024.

12. Nguyen B T, Rodriguez A, Patel N, et al. (December 01, 2020) Conservative Management of Placenta Accreta Using Helium Plasma Focused Radiofrequency Energy: A Surgical Technique. Cureus 12(12): e11832. doi:10.7759/cureus.11832

13. Olawaiye AB. Evaluation of Bowel Injury in a Porcine Model Following Ablation with J-Plasma® Helium-Based Plasma Technology. Biomed J Sci & Tech Res 32(1)-2020. BJSTR. MS.ID.005190.

14. Pedroso JD, Gutierrez MM, Volker W, Howard DL. Thermal Effect of J-Plasma Energy in a Porcine Tissue Model: Implications for Minimally Invasive Surgery. Surg Technol Int. 2017;30:19-24.

15. Smith AV, Kondo MT, Kondo W, Cabrera R. (2018). Laparoscopic Surgical Devices: A Review of the Newest Energies and Instruments. IJMSHR Vol 2, No 06;2018. ISSN: 2581-3366.
16. Sutton C, Abbott J. History of power sources in endoscopic surgery. J Minim Invasive Gynecol. 2013 May-Jun;20(3):271-8. doi: 10.1016/j.jmig.2013.03.001. PMID: 23659747.
17. Theodoulidis V, Prodromidou A, Stamatakis E, Alexakis N, Rodolakis A and Haidopoulos D: Application of J‑Plasma in the excision of diaphragmatic lesions as part of complete cytoreduction in patients with advanced ovarian cancer. Mol Clin Oncol 17: 113, 2022.

RHINOPHYMA

1. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

LOWER BODY

1. Bruno A, Cilluffo M. The role of helium plasma technology in liposuction for lipedema of the lower limbs: a stage-specific analysis. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-05407-5

2. Danilla S, Abou-Kheir N, Gonzalez R, et al. The fourth-generation lower body lift: combining techniques and technologies for improved outcomes in high-demand female patients. Aesthetic Plastic Surgery. 2025;49:3121–3131. doi:10.1007/s00266-025-04877-x

3. Ruff PG IV, Martinez A. Evaluation of the use of the Renuvion system in the labia for labial rejuvenation and volume reduction. J Gynecol Surg. Published online September 29, 2025. doi:10.1177/1042406725138286

4. Tambasco D, Albanese R, Tomaselli F, Pinto V, Pinelli M, De Santis G. Minimizing thighplasty complications: a combined approach of J-medial pattern and helium plasma–assisted liposculpture. Plast Reconstr Surg. 2025;156(2):247-251

SAFETY

1. Barone M, Salzillo R, De Bernardis R, et al. Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in Patients Undergoing Abdominoplasty After Massive Weight Loss: A Prospective Controlled Randomized Study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-024-04655-1

2. Doolabh, V. A single-site Postmarket Retrospective Chart Review of Subdermal Coagulation Procedures with Renuvion. Plastic & Reconstructive Surgery Global Open 2019;7:e2502; 19 November 2019. Doi: 10.1097/GOX.0000000000002502.

3. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

4. Kluska M, Deal RC, Summers K, Chang S. A Retrospective Review Comparing Renuvion Helium Plasma Radiofrequency with BodyTite Bipolar Radiofrequency after Liposuction or Body Contouring. Plastic & Reconstructive Surgery-Global Open 12(8):p e6024, August 2024. | DOI: 10.1097/GOX.0000000000006024

5. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

6. Ruff PG IV, Martinez A. Evaluation of the use of the Renuvion system in the labia for labial rejuvenation and volume reduction. J Gynecol Surg. Published online September 29, 2025. doi:10.1177/1042406725138286

7. Ruff P, Parikh R, Mowlavi A, Zimmerman E and Lebowitz J (2022) Safety of Gynecomastia Procedures in Combination with Helium-Based Plasma Technology: A Retrospective Review. J Aesthet Reconstr Surg Vol.8 No.5: 152.

8. Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

9. Ruff IV, PG, Doolabh V, Zimmerman E, Gentile R. Safety and efficacy of helium plasma for subdermal coagulation. Dermatological Reviews 2020; 1-7. https://doi.org/10.1002/der2.34

10. Shridharani S, Kennedy ML. Safety of Helium-Based Plasma Technology for Coagulation of Soft Tissue: A Retrospective Review, Aesthetic Surgery Journal Open Forum, 2022;, ojac081, https://doi.org/10.1093/asjof/ojac081

11. Shridharani SM, Ruff PG, Doolabh VB, Zimmerman EM. The Safety of Contraction of Subcutaneous Tissue Following Liposuction Procedures. Aesthetic Surgery Journal Open Forum, 2023;, ojad112, https://doi.org/10.1093/asjof/ojad112

12. Tambasco D, Albanese R, Scarabosio A, et al. Ultrasound and helium plasma-assisted liposuction for body contouring: a single-retrospective cohort study of 639 patients. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04367-6.

13. Vanek P. A retrospective evaluation of the safety of combining helium-based plasma radiofrequency technology with ultrasound-assisted lipoabdominoplasty. Aesthet Surg J Open Forum. 2025;7:ojae116. doi:10.1093/asjof/ojae116.

14. Zorrilla AM, Sanchez-Covarrubias AP, Martin K, Rodriguez M. Pain Management and Opioid Consumption After Outpatient Cosmetic Surgery. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221116529

RENUVION ONLY-SUBDERMAL USE

1. Doolabh V, Ruff IV, PG. A Retrospective Chart Review of Subdermal Neck Coagulation Using Helium Plasma Technology. Dermatological Reviews 2020; 1-8. https://doi.org/10.1002/der2.32

2. Lacerna Kimbrell M. Helium plasma radiofrequency brow lift: description of a novel technique and retrospective study on safety, efficacy, and durability. Aesthet Surg J Open Forum. 2025;ojaf031. doi:10.1093/asjof/ojaf031

3. Ruff IV, PG. Thermal Effects of Percutaneous Application of Plasma/Radiofrequency Energy on Porcine Dermis & Fibroseptal Network. JCD, 2020. DOI: 10.1111/jocd.13845

4. Ruff PG, DiBernardo B, Gentile R, Cohen S, Bharti K, Kortesis B, Shridharani S, et al. Safety and Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in the Neck and Submental Region, Aesthetic Surgery Journal, 2023; sjad055, https://doi.org/10.1093/asj/sjad055

5. Ruff PG IV, Martinez A. Evaluation of the use of the Renuvion system in the labia for labial rejuvenation and volume reduction. J Gynecol Surg. Published online September 29, 2025. doi:10.1177/1042406725138286

6. Ruff IV, PG, Vanek P, Nykiel M. Adverse Events of Soft Tissue Coagulation Using a Helium-Based Plasma Technology Alone and in Combination with Ultrasound-Assisted Liposuction, Aesthetic Surgery Journal Open Forum, 2022; https://doi.org/10.1093/asjof/ojac064

7. Sterodimas A, Moutafis A, Nicaretta B, Champsas G. A prospective study on helium-based plasma radiofrequency for minimally invasive breast lift scarless mastopexy. Aesthet Surg J Open Forum. 2025;ojaf004. doi:10.1093/asjof/ojaf004.

8. Sterodimas A, Nicaretta B, Koytsouveli A, et al. Helium-based plasma radio frequency technology for subdermal coagulation in the forehead: a preliminary, single-center retrospective study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-025-04737-8.

SURGICAL, CUTTING, FLAPS

1. Barone M, Salzillo R, De Bernardis R, et al. Efficacy of Renuvion Helium Plasma to Improve the Appearance of Loose Skin in Patients Undergoing Abdominoplasty After Massive Weight Loss: A Prospective Controlled Randomized Study. Aesthetic Plast Surg. 2025. doi:10.1007/s00266-024-04655-1

2. De La Cruz E. Lipoplasty in the Overweight Patient. Clinics in Plastic Surg, 2023, ISSN 0094-1298, https://doi.org/10.1016/j.cps.2023.06.010.

3. Elmore L, Minissale NJ, Israel L, Katz Z, Safran J, Barba A, Austin L, Schaer TP, Freeman TA. Evaluating the Healing Potential of J-Plasma Scalpel-Created Surgical Incisions in Porcine and Rat Models. Biomedicines 2024, 12, 277. https://doi.org/10.3390/biomedicines12020277

4. Gentile RD. Cool Atmospheric Plasma (J-Plasma®) and New Options for Facial Contouring and Skin Rejuvenation of the Heavy Face and Neck. Facial Plast Surg. 2018 Feb;34(1):66-74. doi: 10.1055/s-0037-1621713. Epub 2018 Feb 6.

5. Gentile RD. Laser-Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhytidectomy. Facial Plastic Surgery Clinics of North America, Volume 28, Issue 3, 2020, Pages 379-396, ISSN 1064-7406, ISBN 9780323708395, https://doi.org/10.1016/j.fsc.2020.03.006.

6. Gentile R. The Ultralift: Ultrasound and Energy-Based Facelifting. Advances in Cosmetic Surgery, Vol 5, Issue 1, 2022, pg 63-77. ISSN 2542-4327. ISBN 9780323987851. https://doi.org/10.1016/j.yacs.2022.02.004.

7. Gentile R. Ultrasound-Assisted Rhytidectomy Including Sub-SMAS and Subplatysmal Dissection. Facial Plast Surg 2020; 36(04): 430-446. DOI: 10.1055/s-0040-1714119

8. Jundt JS, Marchena JM, Hanna I, Dhanda J, Breit MJ, Perry AP. Evolving Technologies for Tissue Cutting. Oral Maxillofac Surg Clin North Am. 2019 Nov;31(4):549-559. doi: 10.1016/j.coms.2019.07.009. Epub 2019 Aug 31. PMID: 31481290.

9. Moncada S, Nichols C. Helium Plasma-Assisted Breast Reduction: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac041, https://doi.org/10.1093/asjof/ojac041

10. Palmisano E, Di Biasio G. Minimally invasive management alternative for the treatment of patients with abdominal diastasis and dermal fat flap using the VER tactic: Vaser® + Endoscopy + Renuvion®. Rev Hispanoam Hernia. 2022;10(4):167-171

11. Pinelli M, Starnoni M, De Santis G. The Use of Cold Atmospheric Plasma Device in Flap Elevation. Plast Reconstr Surg Glob Open 2020;8:e2815; doi: 10.1097/GOX.0000000000002815.

12. Skenderian S, Sin Z, Mirzania H, Mowlavi A. Modified Abdominal Skin Resection: A Novel Approach to High-Definition Body Contouring of the Abdomen. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221102301

13. Smith CJ, Watkins AR, Lucas AA, et al. Cold plasma generates a localized inflammatory response and promotes muscle repair. Adv Therap. 2025;8:e00097. doi:10.1002/adtp.202500097

14. Tambasco D, Scarabosio A, Tomaselli F, et al. The role of helium plasma-assisted liposuction in lipoabdominoplasty after weight loss. Aesthet Plast Surg. 2024. doi:10.1007/s00266-024-04542-9.

15. Troell RJ. Lipoabdominoplasty: Comparing Ultrasound-Assisted and Power-Assisted Techniques. The American Journal of Cosmetic Surgery. 2022;0(0). doi:10.1177/07488068221099153

16. Vanek P. A retrospective evaluation of the safety of combining helium-based plasma radiofrequency technology with ultrasound-assisted lipoabdominoplasty. Aesthet Surg J Open Forum. 2025;7:ojae116. doi:10.1093/asjof/ojae116.