The following bibliography of published peer reviewed articles includes uses for our technology as a tool in general and plastic surgery to cut, coagulate and ablate soft tissues. J-Plasma® devices received a general clearance and has not been determined to be safe or effective for use in any specific indication or disease states. This is intended to be a forum for scientific exchange and thus this content may include unapproved uses. All investigator disclosures are within the publications.

Please click on the individual references to learn more.

1. Alletti, et al. Use of Laparoscopic and Laparotomic J-Plasma Handpiece in Gynecological Malignancies: Results From A Pilot Study in A Tertiary Care Center. Front. Oncol., 28 June 2022. Sec. Gynecological Oncology. https://doi.org/10.3389/fonc.2022.868930

2. Barekzi, et al. Effects of Low Temperature Plasma on Prostate Cancer Cells Using the Bovie® Medical J-Plasma Device. Plasma Processes and Polymers. Sept 2016.

3. Elmore L, Minissale NJ, Israel L, Katz Z, Safran J, Barba A, Austin L, Schaer TP, Freeman TA. Evaluating the Healing Potential of J-Plasma Scalpel-Created Surgical Incisions in Porcine and Rat Models. Biomedicines 2024, 12, 277. https://doi.org/10.3390/biomedicines12020277

4. Filis K, Galyfos G, Sigala F, Zografos G. Utilization of Low-Temperature Helium Plasma (J-Plasma) for Dissection and Hemostasis during Carotid Endarterectomy. Journal of Vascular Surgery. March 2020, Volume 6, Issue 1, Pages 152-155.

5. Iavazzo C, Fotiou A, Kokkali K, Vorgias G. Experience With J-Plasma Device in Achieving Complete Cytoreduction in Patients With Ovarian Cancer. Cancer Diagn Progn. 2023 May 3;3(3):392-397. doi: 10.21873/cdp.10230. PMID: 37168972; PMCID: PMC10165381.

6. Jundt JS, Marchena JM, Hanna I, Dhanda J, Breit MJ, Perry AP. Evolving Technologies for Tissue Cutting. Oral Maxillofac Surg Clin North Am. 2019 Nov;31(4):549-559. doi: 10.1016/j.coms.2019.07.009. Epub 2019 Aug 31. PMID: 31481290.

7. Kyriazanos, et al. Total Extraperitoneal Access for Parietal Peritonectomy for Peritoneal Surface Malignancy: The ‘Cocoon’ Technique. European Journal of Obstetrics & Gynecology and Reproductive Biology. June 2020.

8. Llarena NC, Shah AB, Biscotti C, Falcone T, Uy-Kroh MJ. Thermal Injury to the Ovary and Uterus in a Porcine Model: A Comparison of Four Energy Sources. Clin. Exp. Obstet. Gynecol. – ISSN: 0390-6663XLVI, n. 6, 2019 doi: 10.12891/ceog5061.2019

9. Manuel M. Laparoscopic Treatment of Benign and Malignant Pelvic Disorders Utilizing Helium Plasma: A Retrospective Analysis. BioMedical Journal of Scientific & Technical Research. December 23, 2020. DOI: 10.26717/BJSTR.2020.32.005310.

10. Masghati S, Pedroso J, Gutierrez M, Stockwell E, Volker KW, Howard DL. Comparative Thermal Effects of J-Plasma, Monopolar, Argon, and Laser Electrosurgery in a Porcine Tissue Model. Surg Technol Int. 2019;34:35–39.

11. Mattei B, Colletti G, Negrello S, et al. Treating head and neck venous malformations with cold helium plasma electrosurgical device: A 17 patients case series. J Craniofac Surg. 2025. doi:10.1016/j.jcms.2025.02.024.

12. Nguyen B T, Rodriguez A, Patel N, et al. (December 01, 2020) Conservative Management of Placenta Accreta Using Helium Plasma Focused Radiofrequency Energy: A Surgical Technique. Cureus 12(12): e11832. doi:10.7759/cureus.11832

13. Olawaiye AB. Evaluation of Bowel Injury in a Porcine Model Following Ablation with J-Plasma® Helium-Based Plasma Technology. Biomed J Sci & Tech Res 32(1)-2020. BJSTR. MS.ID.005190.

14. Pedroso JD, Gutierrez MM, Volker W, Howard DL. Thermal Effect of J-Plasma Energy in a Porcine Tissue Model: Implications for Minimally Invasive Surgery. Surg Technol Int. 2017;30:19-24.

15. Smith AV, Kondo MT, Kondo W, Cabrera R. (2018). Laparoscopic Surgical Devices: A Review of the Newest Energies and Instruments. IJMSHR Vol 2, No 06;2018. ISSN: 2581-3366.

16. Sutton C, Abbott J. History of power sources in endoscopic surgery. J Minim Invasive Gynecol. 2013 May-Jun;20(3):271-8. doi: 10.1016/j.jmig.2013.03.001. PMID: 23659747.

17. Theodoulidis V, Prodromidou A, Stamatakis E, Alexakis N, Rodolakis A and Haidopoulos D: Application of J‑Plasma in the excision of diaphragmatic lesions as part of complete cytoreduction in patients with advanced ovarian cancer. Mol Clin Oncol 17: 113, 2022.

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